The Senacki Hotel houses 20 single and double guestrooms, including two LUX rooms on three floors and in the penthouse. Each bedroom is equipped with en suite bathrooms or shower, telephone, satellite TV, free access to DVD channels and the Internet, and mini bars. The windows overlooking Grodzka Street offer a breathtaking view of the 17th century Church of SS Peter and Paul (built in the Baroque style) and of the 11th century St. Andrew's Church (one of the oldest place of worship in Krakow). The windows of the other side of the hotel overlook the historical building of the former Wawel Chapter.

In the hotel’s Senacki Restaurant, located in the Column Lounge, guests can order exquisite old Polish style dishes and European meals, complemented by wines from renowned vineyards of France, Italy, Spain and the New World. In addition to this, the building’s cellars - formerly used for merchant stalls - are located on the medieval street level and house a fine cafe and pub.